Maternal Cigarette Smoking and Oral Clefts: A Meta-analysis

1997 ◽  
Vol 34 (3) ◽  
pp. 206-210 ◽  
Author(s):  
Diego F. Wyszynski ◽  
David L. Duffy ◽  
Terri H. Beaty
Keyword(s):  
Cigarette Smoking ◽  
Meta Analysis ◽  
Oral Clefts ◽  
Maternal Cigarette Smoking

Maternal Cigarette Smoking and Oral Clefts: A Meta-analysis

1997 ◽  
Vol 34 (3) ◽  
pp. 206-210 ◽  
Author(s):  
Diego F. Wyszynski ◽  
David L. Duffy ◽  
Terri H. Beaty
Keyword(s):  
Cigarette Smoking ◽  
Cleft Palate ◽  
Cleft Lip ◽  
Meta Analysis ◽  
First Trimester ◽  
Case Control Studies ◽  
Oral Clefts ◽  
Oral Cleft ◽  
Maternal Cigarette Smoking ◽  
Increased Risk

Objective A meta-analysis was performed to estimate the association between maternal cigarette smoking and the risk of having a child with a nonsyndromic oral cleft (NSOC). Design Studies published from 1966 through 1996 were retrieved using MEDLINE, Current Contents, bibliographies, and other sources. MEDLINE and Current Contents search terms included “oral clefts,” “cigarette smoking,” “birth defects,” and “congenital malformations.” Cohort and case-control studies that enrolled oral cleft patients [cleft lip with or without cleft palate (CL/P), cleft palate (CP), or both] and controls, and presented information on maternal cigarette exposure during pregnancy were included in the analysis. Descriptive and outcome data from each study were independently abstracted by two authors. Results The overall odds ratio of the 11 studies satisfying criteria was 1.29 [95% confidence interval (CI), 1.18 to 1.42] for CL/P and 1.32 (95% CI: 1.10 to 1.62) for CP, Indicating a small increased risk of having a child with either a CL/P or a CP for mothers who smoke during the first trimester of the pregnancy. Conclusions These analyses suggest a small but statistically significant association between maternal cigarette smoking during the first trimester of gestation and increased risk of having a child with a CL/P or CP.

scholarly journals Maternal cigarette smoking and oral clefts: a population-based study.

1987 ◽  
Vol 77 (5) ◽  
pp. 623-625 ◽  
Author(s):  
M J Khoury ◽  
A Weinstein ◽  
S Panny ◽  
N A Holtzman ◽  
P K Lindsay ◽  
...  
Keyword(s):  
Cigarette Smoking ◽  
Population Based ◽  
Population Based Study ◽  
Oral Clefts ◽  
Maternal Cigarette Smoking

scholarly journals Maternal Cigarette Smoking during Pregnancy and Risk of Oral Clefts in Newborns

1999 ◽  
Vol 150 (7) ◽  
pp. 683-694 ◽  
Author(s):  
S. Lieff ◽  
A. F. Olshan ◽  
M. Werler ◽  
R. P. Strauss ◽  
J. Smith ◽  
...  
Keyword(s):  
Cigarette Smoking ◽  
Oral Clefts ◽  
Smoking During Pregnancy ◽  
Maternal Cigarette Smoking

MATERNAL CIGARETTE SMOKING DURING PREGNANCY IN RELATION TO ORAL CLEFTS

1990 ◽  
Vol 132 (5) ◽  
pp. 926-932 ◽  
Author(s):  
MARTHA M. WERLER ◽  
EDWARD J. LAMMER ◽  
LYNN ROSENBERG ◽  
ALLEN A. MITCHELL
Keyword(s):  
Cigarette Smoking ◽  
Oral Clefts ◽  
Smoking During Pregnancy ◽  
Maternal Cigarette Smoking

PP - MATERNAL CIGARETTE SMOKING AND RAD51 RS1801321 VARIANT INTERACTIONS ARE ASSOCIATED WITH NONSYNDROMIC ORAL CLEFTS

2017 ◽  
Vol 123 (2) ◽  
pp. e44-e45
Author(s):  
RENATO ASSIS MACHADO ◽  
HELENARA SALVATI BERTOLOSSI MOREIRA ◽  
SIBELE NASCIMENTO DE AQUINO ◽  
SILVIA REGINA DE ALMEIDA REIS ◽  
DARLENE CAMATI PERSUHN ◽  
...  
Keyword(s):  
Cigarette Smoking ◽  
Oral Clefts ◽  
Maternal Cigarette Smoking
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